How does this medication work? What will it do for me?
Acetylsalicylic acid (ASA) belongs to the groups of medications calledanalgesics(pain relievers),antipyretics(fever reducers),anti-inflammatories (inflammation reducers), andplatelet aggregation inhibitors(anticlotting agents). It works by interfering with the production of compounds in the body that cause pain, fever, inflammation, and blood clots.
Acetylsalicylic acid (ASA) is used to relieve pain, fever, and inflammationin various conditions such as lower back and neck pain, the flu, common cold, burns, menstrual pain, headache, migraines, osteoarthritis, rheumatoid arthritis, sprains and strains, nerve pain, toothache, muscle pain,bursitis(inflammation of abursa,a fluid-filled sac located around joints and near the bones), and following surgical and dental procedures. In these situations, ASA is used on an as-needed basis.
Because of the antiplatelet (anticlotting) properties of ASA, it may be used under the supervision of your doctor to:
- prevent a first nonfatal heart attack for people who are at increased risk of having a heart attack as determined by their doctor (factors that increase your risk of heart attack include: smoking, high blood pressure, high cholesterol, inactive lifestyle, stress, and being overweight)
- prevent a second heart attack or stroke
- reduce the risk of complications or death in people with unstable angina
- reduce the risk of "mini-stroke" or transient ischemic attack (TIA)
- reduce the clotting properties of platelets for people who have had carotid artery surgery to prevent the recurrence of TIA and for people receiving hemodialysis through a silicone rubber access
- prevent blood clots for people who have had a total hip replacement
ASA can also be used during a heart attack to reduce the risk of dying from the heart attack.
This medication may be available under multiple brand names and/or in several different forms.Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles.If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor.Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do.It can be harmful for people to take this medication if their doctor has not prescribed it.
What form(s) does this medication come in?
Acetylsalicylic acid by Lil' Drug Store Products is no longer being manufactured for sale in Canada.For brands that may still be available, search under acetylsalicylic acid (ASA). This article is being kept available for reference purposes only.If you are using this medication,speak with your doctor or pharmacist for information about your treatment options.
How should I use this medication?
The recommended dose of ASA for adults varies widely according to the particular condition being treated.
To treat adults with pain or fever, the recommended dose is 325mg to 650mg every 4 to 6hours as needed. The maximum daily dose is 4,000mg, unless otherwise directed by your doctor. ASA should not be used for longer than 5days in a row to treat pain or 3days in a row for fever. Talk to your doctor if either of these conditions persist. For adults with conditions caused by inflammation such as rheumatoid arthritis,the usual dose is 975mg 4 to 6times daily on a regular basis. Sometimes, higher doses may be used.
To treat migraine headache pain,the recommended adult dose is 1,000mg at the onset of pain or symptoms.
To prevent a first nonfatal heart attack, TIA, a second heart attack, or a second stroke,the usual dose for adults is 81mg to 325mg once daily, depending on your doctor's instructions.
During a heart attack,the recommended ASA dose is 160mg to 162mg chewed or crushed. As soon as you suspect you are having a heart attack, call an ambulance and take the recommended ASA dose, providing you have no allergies or other conditions or factors that would indicate ASA is not right for you. This dose should then be continued, under your doctor's supervision, for a month to reduce the risk of a second heart attack.
To prevent blood clotsafter total hip replacement surgery, the recommended dose is 162mg to 325mg taken daily unless otherwise directed by your doctor.
This medication is not recommended to be used by children, teenagers, or young adultsto treat fever(see the section, "Are there any other precautions or warnings for this medication?"). However, if recommended by a doctor in other circumstances such as to treat pain, the recommended dose is 10mg to 15mg per kilogram of body weight every 6 hours as needed to a maximum of 2,400mg per day (ask your doctor or pharmacist to give you the correct dose if you are unsure).
When used as an anti-inflammatory,the recommended dose is 60mg to 125mg per kilogram of body weight daily in 4 to 6 divided doses.
Because ASA can cause stomach irritation and upset, specially coated tablets calledenteric-coatedare recommended when taking ASA for long periods of time. This special coating prevents the tablet from dissolving until it has passed the stomach and moved into the small intestine. This coating also means that it will take longer for the medication to take effect, so do not use enteric-coated tablets when fast relief is required. ASA should also be taken with food to prevent stomach upset. Enteric-coated medications can be taken without food.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications.If your doctor has recommended a dose different from the ones listed here,do not change the way you are taking the medication without talking to your doctor.
It is important that this medication be taken exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature, protect it from moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Who should NOT take this medication?
Do not take acetylsalicylic acid if you:
- are allergic to ASA or any ingredients of the medication
- are in your last trimester of pregnancy
- are prone to bleeding
- are using methotrexate at doses of 15mg or more per week
- have an active gastric ulcer or a history of stomach ulcers
- have had a severe allergic or asthmatic reaction caused by salicylates, ASA, ornonsteroidal anti-inflammatory drugs(NSAIDs; e.g., diclofenac, ibuprofen, indomethacin, naproxen)
- have severe kidney failure
- have severe liver failure
- have severe congestive heart failure
- heartburn or indigestion
- mild-to-moderate abdominal or stomach cramps, pain, or discomfort
- buzzing or ringing in ears
- severe or continuing abdominal or stomach pain, cramping, or burning
- signs of bleeding (e.g., unusual nosebleeds, bruising, blood in urine, coughing blood, bleeding gums, cuts that don't stop bleeding)
- hearing loss
- signs of bleeding in the stomach (e.g., bloody, black, or tarry stools; spitting up of blood; vomiting blood or material that looks like coffee grounds)
- signs of a serious allergic reaction (e.g., abdominal cramps, difficulty breathing, nausea and vomiting, or swelling of the face and throat)
- angiotensin-converting enzyme inhibitors (ACEIs; e.g., fosinopril, lisinopril, ramipril)
- calcium channel blockers (e.g., amlodipine, diltiazem, nifedipine, verapamil)
- corticosteroids (e.g., dexamethasone, hydrocortisone, prednisone)
- diabetes medications (e.g., chlorpropamide, glyburide, insulin, metformin, rosiglitazone)
- herbal products that affect blood clotting (e.g., cat's claw, chamomile, fenugreek, evening primrose, feverfew, garlic, ginger, ginseng, turmeric, white willow)
- influenza vaccine (live)
- loop diuretics (water pills; e.g., bumetanide, furosemide)
- low-molecular-weight heparins (e.g., dalteparin, enoxaparin, tinzaparin)
- multivitamin/mineral supplements
- nonsteroidal anti-inflammatory drugs (NSAIDs; e.g., diclofenac, ibuprofen, indomethacin, naproxen)
- omega-3 fatty acids
- quinolone antibiotics (e.g., ciprofloxacin, norfloxacin, ofloxacin)
- selective serotonin reuptake inhibitors (SSRIs; e.g., citalopram, fluoxetine, paroxetine, sertraline)
- serotonin/norepinephrine reuptake inhibitors (SNRIs; e.g., desvenlafaxine, duloxetine, venlafaxine)
- somatostatin acetate
- sulfonamide antibiotics ("sulfas"; e.g., sulfisoxazole, sulfamethoxazole)
- tetracyclines (e.g., doxycycline, minocycline, tetracycline)
- tricyclic antidepressants (e.g., amitriptyline, clomipramine, desipramine, trimipramine)
- vaccine for chickenpox
- valproic acid and sodium valproate
- vitamin E
- stop taking one of the medications,
- change one of the medications to another,
- change how you are taking one or both of the medications, or
- leave everything as is.
What side effects are possible with this medication?
The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
Stop taking the medication and seek immediate medical attention ifanyof the following occur:
Some people may experience side effects other than those listed.Check with your doctor if you notice any symptom that worries you while you are taking this medication.
Are there any other precautions or warnings for this medication?
Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
HEALTH CANADA ADVISORY
June 8, 2021
Health Canada has issued new information concerning the use of non-steroidal anti-inflammatory drugs (NSAIDs). To read the full Health Canada Advisory, visit Health Canada's web site at www.hc-sc.gc.ca.
Alcohol:People taking ASA on a daily basis are at an increased risk of developing stomach bleeds if they drink alcohol. Avoid or limit your alcohol intake while taking ASA.
Bleeding:ASA has antiplatelet properties, which prevents blood from clotting. This could increase your risk of bleeding. Your doctor will monitor you while you are taking this medication, especially if you are also taking anticoagulant medications (e.g., warfarin). Contact your doctor immediately if you notice any signs of bleeding (e.g., bloody or black, tarry stools, frequent nose bleeds, unexplained bruising).
Breathing problems:People who have asthma, long term breathing problems, or allergic conditions such as hay fever or nasal polyps are more likely to experience difficulty breathing and allergic reactions, caused by ASA. If you have a history of allergic reactions to other substances, or respiratory illness, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Diabetes:Acetylsalicylic acid can increase the effects of certain diabetes medications such as glyburide. High doses of ASA may also reduce blood glucose levels, which may change your insulin needs if you have diabetes.
If you have diabetes or are at risk for developing diabetes, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Glucose-6-phosphate dehydrogenase (G6PD) deficiency: People with G6PD deficiency may experience the breakdown of red blood cells when they take acetylsalicylic acid. The decrease in red blood cells causes anemia. If you have G6PD deficiency, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Gout:Acetylsalicylic acid can increase the level of uric acid in the body, causing gout to flare up. ASA can also decrease the effectiveness of medications used to treat gout. If you have a history of gout or kidney stones, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
If you develop painful, warm and swollen joints or difficulty with urination, contact your doctor as soon as possible.
Kidney function:If you have reduced kidney function or kidney disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Liver function:Decreased liver function or liver disease may cause this medication to build up in the body and cause side effects. If you have decreased liver function or liver disease, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Other medical conditions:If you have a history of stomach ulcers, a tendency to bleed, severely low blood iron levels (anemia), or blood clotting disorders, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Surgery:Acetylsalicylic acid should be stopped at least one week before elective surgery because of the risk of bleeding. If you are scheduled for surgery (including minor surgery, such as dental extractions), talk to your doctor or pharmacist about when you should stop taking ASA.
Pregnancy: When taken in the third trimester of pregnancy, ASA can increase the risk of bleeding for both the mother and child. It can decrease contractions, resulting in delayed or prolonged labour. It may also cause premature (early) closure of thearterial duct(a passageway in the heart) of the fetus. This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately. ASA should not be used by anyone in their last trimester of pregnancy (see the section "Who should NOT take this medication?").
Breast-feeding:Acetylsalicylic acid passes into breast milk. If you are a breast-feeding mother and are taking acetylsalicylic acid, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children:Children, teenagers, and young adults should not take ASA when they have chickenpox, influenza, or flu-like illnesses as it may increase their risk forReye's syndrome,a possibly life-threatening health condition that may cause liver or brain damage.
Seniors: Seniors may be at an increased risk of experiencing side effects of this medication.
What other drugs could interact with this medication?
There may be an interaction between acetylsalicylic acid and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist.Depending on your specific circumstances, your doctor may want you to:
An interaction between two medications does not always mean that you must stop taking one of them.Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with this medication.Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications that you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
All material copyright MediResource Inc. 1996 – 2022. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www.medbroadcast.com/drug/getdrug/ASA-by-Lil-Drug-Store
It works by interfering with the production of compounds in the body that cause pain, fever, inflammation, and blood clots.
Aspirin, an acetylated salicylate (acetylsalicylic acid), is classified among the nonsteroidal antiinflammatory drugs (NSAIDs).
They are chemically related to aspirin, and work by damping down the inflammatory process, so allowing damaged tissue to heal. There are several types of 5-ASA drugs: sulphasalazine (brand name Salazopyrin®) mesalazine (Asacol®, Pentasa®, Salofalk® and Mezavant®).
- heavier-than-normal menstrual bleeding.
- numbness or tingling of hands, feet, or face.
- rash or itching.
- signs of anemia (low red blood cells; e.g., dizziness, pale skin, unusual tiredness or weakness, shortness of breath)
If you are taking aspirin, avoid drinking alcoholic beverages because there is a risk of stomach bleeding. Avoid taking aspirin on an empty stomach, as this can cause heartburn. Take it with water, milk, or food. Do not take any over-the-counter drugs without first getting your doctor's approval.
Cautions with other medicines
medicines to prevent blood clots such as clopidogrel, apixaban, edoxaban, dabigatran, rivaroxaban and warfarin – taking them with aspirin might cause bleeding problems. selective serotonin reuptake inhibitors (SSRIs) such as sertraline, to treat depression.
Aspirin can cause several forms of liver injury: in high doses, aspirin can cause moderate to marked serum aminotransferase elevations occasionally with jaundice or signs of liver dysfunction, and in lower doses in susceptible children with a febrile illness aspirin can lead to Reye syndrome.
Side effects such as stomach upset, nausea, or ulcers may be more likely to occur. Many non-prescription medications contain aspirin, ibuprofen, or naproxen. Always read labels carefully. This medication can cause serious ulcers and bleeding in the stomach.
You should start to feel better 20 to 30 minutes after taking aspirin.
ASA increases your chances of dangerous bleeding because it's a blood thinner. Taking ASA every day can increase your chance of bleeding from your stomach, which is what we call an upper GI bleed. This is dangerous, but we can treat it in the hospital.
Drinking grapefruit juice, cranberry juice, and alcohol during treatment with warfarin can increase your risk of bleeding.
The main side effect of warfarin is bleeding. If you're taking warfarin, you may have trouble stopping the bleeding from a cut on the hand or a nosebleed. More-serious bleeding may be inside the body (internal).
- CBD (cannabidiol)
- Cinnamon (high-dose)
- Digestive enzymes (i.e. papain and bromelain)
- Fish oil.
Aspirin and other NSAIDs may be associated with modest increases in blood pressure. They may diminish the effects of certain antihypertensive agents, including beta blockers, ACE inhibitors and diuretics4.
Aspirin traditionally was assumed to have no effect on blood pressure,5 but in recent studies, aspirin intake at bedtime compared with intake on awakening considerably reduced blood pressure.
WHY MUST I TAKE ASPIRIN WITH A FULL GLASS OF WATER? Aspirin should be taken with a full eight ounces of water to ease swallowing and facilitate absorption of the aspirin.
Interactions between your drugs
No interactions were found between aspirin and Vitamins.
In most cases, it's usually fine to continue to enjoy your coffee and take your daily aspirin. To be on the safe side, though, wash it down with a glass of water before you enjoy that first sip of coffee. Your stomach will thank you.
But does it matter when during the day you take the drug? A new Dutch study suggests that people who take aspirin at bedtime might get more protection against heart attacks or strokes. The research involved nearly 300 heart attack survivors who were taking aspirin to ward off a second heart attack.
The plasma half-life of aspirin is only 20 minutes; however, because platelets cannot generate new COX, the effects of aspirin last for the duration of the life of the platelet (≈10 days). After a single dose of aspirin, platelet COX activity recovers by ≈10% per day as a function of platelet turnover.
About aspirin to prevent blood clots.
|Type of medicine||An antiplatelet medicine|
|Used for||To prevent clots from forming in blood vessels|
- Abdominal swelling (ascites)
- Enlarged blood vessels just beneath the skin's surface.
- Enlarged spleen.
- Red palms.
- Yellowing of the skin and eyes (jaundice)
Aspirin has been known to help people living with some diseases of the heart and blood vessels. It can help prevent a heart attack or clot-related stroke by interfering with how the blood clots.
When taken as directed, regular use of aspirin does not seem to increase the risk of kidney disease in people who have normal kidney function. However, taking doses that are too large (usually more than six or eight tablets a day) may temporarily and possibly permanently reduce kidney function.
Examples of common medications that can disturb your sleep include the following: Nasal decongestants. Aspirin-containing preparations. Pain relievers with caffeine.
This class of medications includes:
- Aspirin (full dose)
- Celecoxib (used in Celebrex)
- Diclofenac (used in Votaren)
- Ibuprofen (used in Advil or Motrin)
- Naproxen (used in Aleve)
Do not lie down immediately after taking medicine, to make sure the pills have gone through the esophagus into the stomach. Notify your healthcare provider if you experience painful swallowing or feel that the medicine is sticking in your throat.
Low doses of aspirin — such as 75 to 100 milligrams (mg), but most commonly 81 mg —can be effective at preventing heart attack or stroke. Health care providers usually prescribe a daily dose between 75 mg and 325 mg (a regular-strength tablet).
Health experts warn bleeding risks can outweigh cardiovascular benefits. Adults 60 and older should not start taking aspirin to lower their risk of a first heart attack or stroke, according to final recommendations issued April 26 by the U.S. Preventive Services Task Force.
Symptoms of thin blood include :
- slow wound clotting.
- bleeding gums.
- blood in the stools.
- heavy menstrual flow without clots.
Symptoms of a blood clot include: throbbing or cramping pain, swelling, redness and warmth in a leg or arm. sudden breathlessness, sharp chest pain (may be worse when you breathe in) and a cough or coughing up blood.
Grapefruit and other citrus fruits can interfere with how your body metabolizes these medications.
Natural Aids in Thinning Blood
Meanwhile there are fruits that can aid in blood thinning. These include blueberries, cherries, cranberries, grapes, oranges, prunes, raisins, strawberries and tangerines.
Diet when taking blood thinners | Ohio State Medical Center - YouTube
What blood thinners do
- clopidogrel (Plavix)
- dipyridamole (Persantine)
- ticlopidine (Ticlid)
Blood thinner treatment for PE is usually advised for at least 3-6 months. Your healthcare provider may advise a longer course depending on why you had the blood clot. Some people at high risk of blood clots may stay on blood thinner indefinitely.
Because you are taking a blood thinner, you should try not to hurt yourself and cause bleeding. You need to be careful when you use knives, scissors, razors, or any sharp object that can make you bleed. You also need to avoid activities and sports that could cause injury. Swimming and walking are safe activities.
Both the National Institutes of Health Office of Dietary Supplements and the Agency for Healthcare Research and Quality do not list any negative interactions between vitamin D supplements and blood thinners.
If you take blood thinners, such as Coumadin, Plavix, or Eliquis, your doctor may recommend taking Tylenol for pain as opposed to aspirin or ibuprofen.
Fruits to Consume
There are several fruits that have no vitamin K that would interact with warfarin. You can eat citrus fruits and juices, including tangerines, oranges and clementines, without side effects.
The American Society of Anesthesiologists (
Asa is a gender-neutral name of Hebrew origin, meaning “doctor, healer.” The name Asa stems from the Biblical mention of King Asa, the third ruler of Judah and fifth king of the House of David.
Associates in Science and Arts. Criminal Justice/Law Enforcement (ASA)
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Technically the ASA status, an assessment of the severity of preoperative co- morbid illnesses, does not include age as a criterion.
ASA III. A patient with severe systemic disease Substantive functional limitations; One or more moderate to severe diseases.
How common is the name Asa for a baby born in 2021? Asa was the 496th most popular boys name and 2060th most popular girls name. In 2021 there were 586 baby boys and only 92 baby girls named Asa. 1 out of every 3,175 baby boys and 1 out of every 19,342 baby girls born in 2021 are named Asa.
How to Pronounce Asa? (CORRECTLY) - YouTube
What is the difference between a lawyer and an attorney? It is helpful to remember that all attorneys are lawyers, but not all lawyers are attorneys. The major difference is that attorneys can represent clients in court and other legal proceedings, while lawyers cannot.
Aksjeselskap is the Norwegian term for a stock-based company. It is usually abbreviated AS, historically often written as A/S. An AS is always a limited company, i.e. the owners cannot be held liable for any debt beyond the stock capital.
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Many photographic chemicals use non-biodegradable compounds, such as EDTA, DTPA, NTA and borate. EDTA, DTPA, and NTA are very often used as chelating agents in all processing solutions, particularly in developers and washing aid solutions.
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